- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Baboon, Chimpanzee, Cynomolgus, Human, Pig, Rhesus
- IMMUNOGEN: Rheumatoid synovial cells and human monocytes
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow
- APPLICATION NOTE: CD11b Antibody [ICRF44] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.
- SPECIFICITY: CD11b
- CLONALITY: Monoclonal
- ISOTYPE: IgG1
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
- CONCENTRATION: 0.1 mg/mL
- STORAGE CONDITIONS: Store vial at 2-8°C
- NCBI OFFICIAL SYMBOL: ITGAM
- ADDITIONAL NAMES: Mac-1alpha, Mo-1, CR3, integrin alphaM, C3biR, ITGAM, CR3A, p170
- Protein Accession Number: P11215
- NCBI GENE ID NUMBER: 3684
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
- CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).
- FOR RESEARCH USE ONLY
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- Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CATALOG NUMBER: 99-461
- Size: 0.1 mg
- List Price: $235.00
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