Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
- IMMUNOGEN: This CCNK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human CCNK.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 64 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: CCNK
- ADDITIONAL NAMES: Cyclin-K, CCNK, CPR4
- Protein Accession Number: O75909
- NCBI GENE ID NUMBER: 8812
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is a member of thetranscription cyclin family. These cyclins may regulatetranscription through their association with and activation ofcyclin-dependent kinases (CDK) that phosphorylate the C-terminaldomain (CTD) of the large subunit of RNA polymerase II. This geneproduct may play a dual role in regulating CDK and RNA polymeraseII activities.
- 1: Marsaud, V., et al. Mol. Cancer 9, 103 (2010) :
- 2: Baek, K., et al. J. Mol. Biol. 366(2):563-573(2007)
- 3: Olsen, J.V., et al. Cell 127(3):635-648(2006)
- 4: Olsen, J.V., et al. Cell 127(3):635-648(2006)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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