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- SPECIES: Mouse
- SOURCE SPECIES: CHO cells
- RECOMBINANT PROTEIN SEQUENCE: The extracellular domain of mouse CCL22 (aa 25-92) is fused to the N-terminus of the Fc region of mouse IgG2a.
- FUSION TAG: Fc Tag
- APPLICATION NOTE: This recombinant proteins is for research use only.
Properties
- PURITY: >98% (SDS-PAGE).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza). - PHYSICAL STATE: Lyophilized
- BUFFER: Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
- STORAGE CONDITIONS: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Additional Info
- NCBI OFFICIAL SYMBOL: Ccl22
- ADDITIONAL NAMES: C-C Motif Chemokine 22, CC Chemokine STCP-1, Stimulated T Cell Chemotactic Protein 1, STCP1, MDC, Macrophage-derived Chemokine, Small-inducible Cytokine A22
- Protein Accession Number: NP_033163
- PROTEIN GI NUMBER: 6677879
- NCBI GENE ID NUMBER: 20299
Background
- CCL22 (C-C Motif Chemokine 22; Stimulated T cell chemotactic protein; STCP1) is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilization in dendritic cells, IL-2 activated NK cells and activated T lymphocytes.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Shipping Info
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