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CBX5 Antibody [D2G7]
CBX5 Antibody [D2G7]
CBX5 Antibody [D2G7]
CBX5 Antibody [D2G7]
CBX5 Antibody [D2G7]
CBX5 Antibody [D2G7]
CBX5 Antibody [D2G7]

CBX5 Antibody [D2G7]

CATALOG NUMBER: 13-998
  • Clonality: Monoclonal
  • Tested Applications: IF, IHC, IP, WB
  • Host Species: Rabbit
  • Species Reactivity: Human, Mouse, Rat
  • Conjugate: Unconjugated

Specifications

  • HOST SPECIES: Rabbit
  • SPECIES REACTIVITY: Human, Mouse, Rat
  • IMMUNOGEN: Recombinant protein of human CBX5
  • CONJUGATE: Unconjugated
  • TESTED APPLICATIONS: IF, IHC, IP, WB
  • APPLICATION NOTE: WB: 1:500 - 1:2000
    IHC: 1:50 - 1:200
    IF: 1:50 - 1:200
    IP: 1:20 - 1:50
  • POSITIVE CONTROL 1: MCF7
  • POSITIVE CONTROL 2: HeLa
  • PREDICTED MOLECULAR WEIGHT: Observed: 22kDa

Properties

  • PURIFICATION: Affinity purification
  • CLONALITY: Monoclonal
  • ISOTYPE: IgG
  • PHYSICAL STATE: Liquid
  • BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • CONCENTRATION: batch dependent
  • STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.

Additional Info

  • NCBI OFFICIAL SYMBOL: CBX5
  • ADDITIONAL NAMES: CBX5, HP1, HP1A, HEL25
  • NCBI GENE ID NUMBER: 23468
  • USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background

  • This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER: 13-998

    Product Discontinued. Please contact us for alternate product(s).

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