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CAV1 Antibody [D3C2]
CAV1 Antibody [D3C2]
CAV1 Antibody [D3C2]
CAV1 Antibody [D3C2]
CAV1 Antibody [D3C2]

CAV1 Antibody [D3C2]

CATALOG NUMBER: 13-796
  • Clonality: Monoclonal
  • Tested Applications: IF, IHC, WB
  • Host Species: Rabbit
  • Species Reactivity: Human
  • Conjugate: Unconjugated

Specifications

  • HOST SPECIES: Rabbit
  • SPECIES REACTIVITY: Human
  • IMMUNOGEN: Recombinant protein of human CAV1
  • CONJUGATE: Unconjugated
  • TESTED APPLICATIONS: IF, IHC, WB
  • APPLICATION NOTE: WB: 1:500 - 1:2000
    IHC: 1:50 - 1:200
    IF: 1:50 - 1:200
  • POSITIVE CONTROL 1: A-431
  • PREDICTED MOLECULAR WEIGHT: Observed: 20kDa

Properties

  • PURIFICATION: Affinity purification
  • CLONALITY: Monoclonal
  • ISOTYPE: IgG
  • PHYSICAL STATE: Liquid
  • BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • CONCENTRATION: batch dependent
  • STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.

Additional Info

  • NCBI OFFICIAL SYMBOL: CAV1
  • ADDITIONAL NAMES: Caveolin-1 Antibody: Caveolin-1, BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
  • NCBI GENE ID NUMBER: 857
  • USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background

  • The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER: 13-796

    Product Discontinued. Please contact us for alternate product(s).

    Datasheet
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