Specifications
- HOST SPECIES: Goat
- SPECIES REACTIVITY: Human
- HOMOLOGY: Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
- IMMUNOGEN: The immunogen for this antibody is: NRKVSQRRVDFCKDP
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, WB
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 33kDa band observed in Human Colon lysates (calculated MW of 33.3kDa according to NP_001217.2). Recommended concentration: 0.5-1.5ug/ml.
- SPECIFICITY: This antibody is expected to recognize reproted isoform alpha (NP_001217.2) only. The immunizing peptide overlaps phosphorylated serine 257 and therefore this antibody is not expected to recognize the phosphorylated protein.
- PREDICTED MOLECULAR WEIGHT: Approx 33kDa
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: Caspase 6
- ADDITIONAL NAMES: CASP6, caspase 6, apoptosis-related cysteine peptidase, MCH2, apoptotic protease MCH-2, caspase 6, apoptosis-related cysteine protease, caspase-6
- Protein Accession Number: NP_001217.2,NP_116787.1
- PROTEIN GI NUMBER: 14916483
- NCBI GENE ID NUMBER: 839
Background
- 1: Stanger K, Steffek M, Zhou L, Pozniak CD, Quan C, Franke Y, Tom J, Tam C, Elliott JM, Lewcock JW, Zhang Y, Murray J, Hannoush RN.Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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