CABLES1 Antibody
CATALOG NUMBER: 13-587- Clonality: Polyclonal
- Tested Applications: IHC, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 50 uL
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, WB
- APPLICATION NOTE: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200 - POSITIVE CONTROL 1: MCF7
- POSITIVE CONTROL 2: HT-29
- POSITIVE CONTROL 3: A-549
- POSITIVE CONTROL 4: HL-60
- POSITIVE CONTROL 5: HeLa
- POSITIVE CONTROL 6: Mouse brain
- PREDICTED MOLECULAR WEIGHT: Observed: 67kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: CABLES1
- ADDITIONAL NAMES: CABL1, CABLES, HsT2563, IK3-1, CDK5 and ABL1 enzyme substrate 1, interactor with CDK3 1
- NCBI GENE ID NUMBER: 91768
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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