Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human BTN3A1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 58 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: BTN3A1
- ADDITIONAL NAMES: Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5
- Protein Accession Number: O00481
- NCBI GENE ID NUMBER: 11119
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The butyrophilin (BTN) genes are a group of majorhistocompatibility complex (MHC)-associated genes that encode typeI membrane proteins with 2 extracellular immunoglobulin (Ig)domains and an intracellular B30.2 (PRYSPRY) domain. Threesubfamilies of human BTN genes are located in the MHC class Iregion: the single-copy BTN1A1 gene (MIM 601610) and the BTN2(e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, whichhave undergone tandem duplication, resulting in 3 copies of each(summary by Smith et al., 2010 [PubMed 20208008]).[supplied byOMIM].
- 1: Smith, I.A., et al. J. Immunol. 184(7):3514-3525(2010)
- 2: Shi, J., et al. Nature 460(7256):753-757(2009)
- 3: Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
- 4: Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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