- KO
beta 2 Microglobulin Antibody, KO Validated
CATALOG NUMBER: 14-403- Clonality: Polyclonal
- Tested Applications: IHC, IP, WB
- Host Species: Rabbit
- Species Reactivity: Human, Monkey, Mouse, Rat
- Conjugate: Unconjugated
- Size: 50 uL
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Monkey, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human beta 2 Microglobulin (NP_004039.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, IP, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IP: 1:50 - 1:100 - POSITIVE CONTROL 1: Jurkat
- POSITIVE CONTROL 2: COS7
- POSITIVE CONTROL 3: HeLa
- POSITIVE CONTROL 4: K-562
- POSITIVE CONTROL 5: Mouse liver
- POSITIVE CONTROL 6: Mouse spleen
- PREDICTED MOLECULAR WEIGHT: Observed: 12kDa
Advanced Validation
- VALIDATION: Antibody is Knockout validated.
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: B2M
- ADDITIONAL NAMES: B2M Antibody: Beta-2-microglobulin
- NCBI GENE ID NUMBER: 567
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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