- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 20-247 of human BDNF (NP_733928.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IHC, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
- POSITIVE CONTROL 1: A-549
- POSITIVE CONTROL 2: SW480
- POSITIVE CONTROL 3: Mouse kidney
- POSITIVE CONTROL 4: Mouse brain
- POSITIVE CONTROL 5: Rat brain
- PREDICTED MOLECULAR WEIGHT: Observed: 14kDa
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
- NCBI OFFICIAL SYMBOL: BDNF
- ADDITIONAL NAMES: BDNF , brain-derived neurotrophic factor, MGC34632, neurotrophin
- NCBI GENE ID NUMBER: 627
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
- This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
- FOR RESEARCH USE ONLY
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- Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CATALOG NUMBER: 14-776
- Size: 50 uL
- List Price: $285.00
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