Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BCL2 (NP_000624.2).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, IP, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IP: 1:50 - 1:100 - POSITIVE CONTROL 1: HL-60
- POSITIVE CONTROL 2: Jurkat
- POSITIVE CONTROL 3: HeLa
- POSITIVE CONTROL 4: Mouse lung
- POSITIVE CONTROL 5: Mouse testis
- POSITIVE CONTROL 6: Rat liver
- PREDICTED MOLECULAR WEIGHT: Observed: 28kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: BCL2
- ADDITIONAL NAMES: Bcl-2 Antibody: Bcl-2, PPP1R50, Apoptosis regulator Bcl-2
- NCBI GENE ID NUMBER: 596
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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