Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: B-RAF (phospho Thr599) antibody was raised against a peptide sequence around phosphorylation site of threonine 599 (L-A-T (p)-V-K) derived from Human B-RAF.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC
- SPECIFICITY: The antibody detects endogenous levels of B-Raf only when phosphorylated at threonine 598.
- PREDICTED MOLECULAR WEIGHT: 84 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: BRAF
- ADDITIONAL NAMES: B-RAF, RAFB1, RMIL, BRAF1, c-RMIL
- Protein Accession Number: NP_004324.2
- PROTEIN GI NUMBER: 50403720
- NCBI GENE ID NUMBER: 673
Background
- Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.
- 1: Armelle Calipel, J. Biol. Chem., Oct 2003; 278: 42409 - 42418.
- 2: Tara J. Dillon, J. Biol. Chem., Sep 2003; 278: 35940 - 35949.
- 3: R K Jaiswal, Mol. Cell. Biol., Oct 1994; 14: 6944 - 6953.
- 4: Laura L. Dugan, J. Biol. Chem., Sep 1999; 274: 25842.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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