Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This ARHGEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the N-terminal region of human ARHGEF1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 102 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ARHGEF1
- ADDITIONAL NAMES: Rho guanine nucleotide exchange factor 1, 115 kDa guanine nucleotide exchange factor, p115-RhoGEF, p115RhoGEF, Sub15, ARHGEF1
- Protein Accession Number: Q92888
- PROTEIN GI NUMBER: 34395524
- NCBI GENE ID NUMBER: 9138
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein may formcomplex with G proteins and stimulate Rho-dependent signals.Multiple alternatively spliced transcript variants have been foundfor this gene, but the full-length nature of some variants has notbeen defined.
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Loirand, G., et al. Med Sci (Paris) 26 (6-7), 561-563 (2010) :
- 3: Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
- 4: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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