Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Rat
- IMMUNOGEN: This AQP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human AQP1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 29 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: AQP1
- ADDITIONAL NAMES: Aquaporin-1, AQP-1, Aquaporin-CHIP, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule, AQP1, CHIP28
- Protein Accession Number: P29972
- PROTEIN GI NUMBER: 267412
- NCBI GENE ID NUMBER: 358
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Aquaporins are a family of small integral membraneproteins related to the major intrinsic protein (MIP or AQP0). Thisgene encodes an aquaporin which functions as a molecular waterchannel protein. It is a homotetramer with 6 bilayer spanningdomains and N-glycosylation sites. The protein physically resembleschannel proteins and is abundant in erythrocytes and renal tubes.The gene encoding this aquaporin is a possible candidate fordisorders involving imbalance in ocular fluid movement. Severaltranscript variants encoding different isoforms have been found forthis gene.
- 1: Chen, L.M., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299 (5), R1163-R1174 (2010) :
- 2: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 3: Shankardas, J., et al. Mol. Vis. 16, 1538-1548 (2010) :
- 4: Halverson, G.R., et al. Immunohematology 26(1):22-26(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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