- Recombinant
Apolizumab (HLA-DRB) Antibody, Monoclonal
CATALOG NUMBER: 10-067- Clonality: Recombinant Monoclonal
- Conjugate: Unconjugated
- Size: 0.1 mg
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- SOURCE SPECIES: CHO cells
- IMMUNOGEN: Humanized / HLA-DRB [Homo sapiens]
- CONJUGATE: Unconjugated
Properties
- PURIFICATION: >95%
- CLONALITY: Recombinant Monoclonal
- ISOTYPE: IgG1-nd
- BUFFER: PBS buffer pH7.5
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage.
Additional Info
- ADDITIONAL NAMES: Hu1D10, HLA-DRB, HLA-DRB
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.Apolizumab is a humanized monoclonal antibody directed against 1D10,a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells.Apolizumab induces complement-mediated cytotoxicity,antibody-dependent cell-mediated cytotoxicity,and apoptosis of 1D10 antigen-positive B cells in vitro.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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