Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
- IMMUNOGEN: This AP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human AP2S1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 17 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: AP2S1
- ADDITIONAL NAMES: AP-2 complex subunit sigma, Adaptor protein complex AP-2 subunit sigma, Adaptor-related protein complex 2 subunit sigma, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, HA2 17 kDa subunit, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin, AP2S1, AP17, CLAPS2
- Protein Accession Number: P53680
- PROTEIN GI NUMBER: 51338780
- NCBI GENE ID NUMBER: 1175
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- One of two major clathrin-associated adaptor complexes,AP-2, is a heterotetramer which is associated with the plasmamembrane. This complex is composed of two large chains, a mediumchain, and a small chain. This gene encodes the small chain of thiscomplex. Alternative splicing has been observed in this gene andresults in two known transcripts.
- 1: Stove, V., et al. J. Virol. 79(17):11422-11433(2005)
- 2: Lu, W., et al. Neuron 47(3):407-421(2005)
- 3: Collins, B.M., et al. Cell 109(4):523-535(2002)
- 4: Yano, H., et al. J. Neurosci. 21 (3), RC125 (2001) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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