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- SPECIES: Human
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: Ala2-Asp320
- FUSION TAG: Tag Free
- APPLICATION NOTE: This recombinant protein can be used for biological assays. For research use only.
- PREDICTED MOLECULAR WEIGHT: 35.9 kD
Properties
- PURITY: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. - PHYSICAL STATE: Liquid
- BUFFER: Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 1mM DTT, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
- STORAGE CONDITIONS: Store at -20°C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: ANXA5
- ADDITIONAL NAMES: Annexin A5, Anchorin CII, Annexin V, Annexin-5, Calphobindin I, CBP-I, Endonexin II, Lipocortin V, Placental Anticoagulant Protein 4, PP4, Placental Anticoagulant Protein I, PAP-I, Thromboplastin Inhibitor, Vascular Anticoagulant-Alpha, VAC-Alpha, ANXA5, ANX5, ENX2
- Protein Accession Number: P08758
- NCBI GENE ID NUMBER: 308
Background
- Annexin A5 (ANXA5) is a member of the annexin family of calcium-dependent phospholipid binding proteins. ANXA5 is an anticoagulant protein by acting as an indirect inhibitor of the thromboplastin-specific complex. ANXA5 is also a protein kinase C and phospholipase A2 inhibitor. It participate in inflammation, cellular signal transduction, growth and differentiation. ANXA5 binding to phosphatidylserine and sulfatide to regulates coagulability in the blood stream. It also protects sinsuoidal endothelial cells from ischemia reperfusion damage. ANXA5 is important for normal CFTR chloride channel activity.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.
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