- SPECIES: Human, Mouse
- SOURCE SPECIES: HEK293 cells
- RECOMBINANT PROTEIN SEQUENCE: Mouse angiopoietin-2 (aa 19-496) is fused at the N-terminus to a DDDDK-tag.
- FUSION TAG: DDDDK Tag
- APPLICATION NOTE: This recombinant proteins is for research use only.
- PURITY: >95% (SDS-PAGE).
Endotoxin level is less than 0.05EU/ μg purified protein (LAL test; Lonza).
- PHYSICAL STATE: Lyophilized
- BUFFER: Contains PBS with trehalose and Brij35. Reconstitute with 100 μl sterile water.
- CONCENTRATION: 0.1 mg /ml after reconstitution.
- STORAGE CONDITIONS: Stable for at least 6 months after receipt when stored at -20°C.
- NCBI OFFICIAL SYMBOL: Angpt2
- ADDITIONAL NAMES: Ang-2, Ang2, Angpt2, Agpt2
- Protein Accession Number: O35608
- PROTEIN GI NUMBER: 46577675
- NCBI GENE ID NUMBER: 11601
- Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
- FOR RESEARCH USE ONLY
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- Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
CATALOG NUMBER: 90-311
- Size: 10 ug
- List Price: $310.00
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