Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: A synthetic peptide corresponding to the N terminus.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC, WB
- APPLICATION NOTE: ELISA, Western (immuno) blotting, Immunostaining (in testing)
Properties
- PURIFICATION: Affinity Purified
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- CONCENTRATION: batch dependent
Additional Info
- NCBI OFFICIAL SYMBOL: Aadat
- ADDITIONAL NAMES: 2 aminoadipate aminotransferase, 2 aminoadipate transaminase, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Aadat, AadAT, AADAT_HUMAN, Aadt, AI875679, Alpha aminoadipate aminotransferase, Alpha-aminoadipate aminotransferase, EC 2.6.1.39, EC 2.6.1.7, KAT/AadAT, KAT2, KATII, Kat2, mKat-2
- Protein Accession Number: NP_035964
- PROTEIN GI NUMBER: 46396046
- NCBI GENE ID NUMBER: 23923
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Kynurenine aminotransferase II (KATII) is the major enzyme responsible for the synthesis of the endogenous neuroprotectant kynurenic acid in the brain.
- 1: Guidetti, P., Okuno, E. and Schwarcz, R. 1998. Characterization of rat brain kynurenine aminotransferases I and II. J. Neurosci. Res. 50: 457-465
- 2: Rzeski, W., Kocki, T., Dybel, A., Wejksza, K., Zdzisinska, B., Kandefer-Szerszen, M., Turski, W.A., Okuno, E. and Albrecht, J. 2005. Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in cultured cerebral cortical neurons. J. Neurosci. Res. 80:677-682
- 3: Buchli R, Alberati-Giani D, Malherbe P, Kohler C, Broger C et al. (1995) Cloning and functional expression of a soluble form of kynurenine/ alpha-aminoadipate aminotransferase from rat kidney. J Biol Chem 270, 29330-29335
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
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