AMFR Antibody
CATALOG NUMBER: 58-127- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This AMFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the Central region of human AMFR.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 73 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: AMFR
- ADDITIONAL NAMES: E3 ubiquitin-protein ligase AMFR, 632-, Autocrine motility factor receptor, AMF receptor, RING finger protein 45, gp78, AMFR, RNF45
- Protein Accession Number: Q9UKV5
- PROTEIN GI NUMBER: 34922250
- NCBI GENE ID NUMBER: 267
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Autocrine motility factor is a tumor motility-stimulatingprotein secreted by tumor cells. The protein encoded by this geneis a glycosylated transmembrane protein and a receptor forautocrine motility factor. The receptor, which shows some sequencesimilarity to tumor protein p53, is localized to the leading andtrailing edges of carcinoma cells.
- 1: Joshi, B., et al. J. Biol. Chem. 285(12):8830-8839(2010)
- 2: Bernardi, K.M., et al. Mol. Biol. Cell 21(1):140-151(2010)
- 3: Ballar, P., et al. Int. J. Biochem. Cell Biol. 42(1):167-173(2010)
- 4: Shmueli, A., et al. Biochem. Biophys. Res. Commun. 390(3):758-762(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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