ALG11 Antibody
CATALOG NUMBER: 59-672- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This ALG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-468 amino acids from the C-terminal region of human ALG11.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 56 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ALG11
- ADDITIONAL NAMES: GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase, ALG11, GT8
- Protein Accession Number: Q2TAA5
- PROTEIN GI NUMBER: 156631015
- NCBI GENE ID NUMBER: 440138
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes aGDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase whichis localized to the cytosolic side of the endoplasmic reticulum(ER) and catalyzes the transfer of the fourth and fifth mannoseresidue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol andMan4GlcNAc2-PP-dolichol resulting in the production ofMan5GlcNAc2-PP-dolichol. Mutations in this gene are associated withcongenital disorder of glycosylation type Ip (CDGIP). This geneoverlaps but is distinct from the UTP14, U3 small nucleolarribonucleoprotein, homolog C (yeast) gene. A pseudogene of theGDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase hasbeen identified on chromosome 19.
- 1: Rind, N., et al. Hum. Mol. Genet. 19(8):1413-1424(2010)
- 2: Rohozinski, J., et al. Biol. Reprod. 74(4):644-651(2006)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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