Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This AHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 555-582 amino acids from the Central region of human AHR.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IF, IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 96 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: AHR
- ADDITIONAL NAMES: Aryl hydrocarbon receptor, Ah receptor, AhR, Class E basic helix-loop-helix protein 76, bHLHe76, AHR, BHLHE76
- Protein Accession Number: P35869
- PROTEIN GI NUMBER: 3041653
- NCBI GENE ID NUMBER: 196
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- AHR is a ligand-activated transcription factorinvolved in the regulation of biological responses to planararomatic hydrocarbons. This receptor has been shown to regulatexenobiotic-metabolizing enzymes such as cytochrome P450. Itsligands included a variety of aromatic hydrocarbons. [provided byRefSeq].
- 1: Davila, S., et al. Genes Immun. (2010) In press :
- 2: Kalthoff, S., et al. J. Biol. Chem. 285(9):5993-6002(2010)
- 3: Hall, J.M., et al. Mol. Endocrinol. 24(2):359-369(2010)
- 4: Schroeder, J.C., et al. Biochemistry 49(2):393-400(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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