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AFP Antibody [F3B0]
CATALOG NUMBER: 14-176- Clonality: Monoclonal
- Tested Applications: IF, IHC, WB
- Host Species: Mouse
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 50 uL
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant protein of human AFP
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IHC, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200 - POSITIVE CONTROL 1: HepG2
- POSITIVE CONTROL 2: human plasma
- POSITIVE CONTROL 3: SH-SY5Y
- POSITIVE CONTROL 4: mouse plasma
- POSITIVE CONTROL 5: mouse liver
- POSITIVE CONTROL 6: mouse kidney
- PREDICTED MOLECULAR WEIGHT: Observed: 69kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Monoclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: AFP
- ADDITIONAL NAMES: AFP Antibody: FETA, HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein
- NCBI GENE ID NUMBER: 174
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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