Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This ADORA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the C-terminal region of human ADORA1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 37 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ADORA1
- ADDITIONAL NAMES: Adenosine receptor A1, ADORA1
- Protein Accession Number: P30542
- PROTEIN GI NUMBER: 231473
- NCBI GENE ID NUMBER: 134
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is an adenosine receptorthat belongs to the G-protein coupled receptor 1 family. There are3 types of adenosine receptors, each with a specific pattern ofligand binding and tissue distribution, and together they regulatea diverse set of physiologic functions. The type A1 receptorsinhibit adenylyl cyclase, and play a role in the fertilizationprocess. Animal studies also suggest a role for A1 receptors inkidney function and ethanol intoxication. Transcript variants withalternative splicing in the 5' UTR have been found for this gene.
- 1: Lane, J.R., et al. Biochem. Pharmacol. 80(8):1180-1189(2010)
- 2: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 3: Wagner, A.K., et al. Epilepsy Res. 90(3):259-272(2010)
- 4: Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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