ADNP Antibody
CATALOG NUMBER: 59-817- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-860 amino acids from the C-terminal region of human ADNP.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 124 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ADNP
- ADDITIONAL NAMES: Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein, ADNP, ADNP1, KIAA0784
- Protein Accession Number: Q9H2P0
- PROTEIN GI NUMBER: 24636245
- NCBI GENE ID NUMBER: 23394
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Vasoactive intestinal peptide is a neuroprotective factorthat has a stimulatory effect on the growth of some tumor cells andan inhibitory effect on others. This gene encodes a protein that isupregulated by vasoactive intestinal peptide and may be involved inits stimulatory effect on certain tumor cells. The encoded proteincontains one homeobox and nine zinc finger domains, suggesting thatit functions as a transcription factor. This gene is alsoupregulated in normal proliferative tissues. Finally, the encodedprotein may increase the viability of certain cell types throughmodulation of p53 activity. Alternatively spliced transcriptvariants encoding the same protein have been described. [providedby RefSeq].
- 1: Braitch, M., et al. Neuroimmunomodulation 17(2):120-125(2010)
- 2: Mandel, S., et al. J. Biol. Chem. 282(47):34448-34456(2007)
- 3: Wu, C., et al. Proteomics 7(11):1775-1785(2007)
- 4: Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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