Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse, Rat
- IMMUNOGEN: This ADCY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-481 amino acids from the Central region of human ADCY2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 124 kDa
Properties
- PURIFICATION: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ADCY2
- ADDITIONAL NAMES: Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, ADCY2, KIAA1060
- Protein Accession Number: Q08462
- PROTEIN GI NUMBER: 118572617
- NCBI GENE ID NUMBER: 108
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the family of adenylatecyclases, which are membrane-associated enzymes that catalyze theformation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and isstimulated by the G protein beta and gamma subunit complex.
- 1: Halls, M.L., et al. EMBO J. 29(16):2772-2787(2010)
- 2: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 3: Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
- 4: Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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