- Trial Size
ADAM29 Antibody
CATALOG NUMBER: 8183- Clonality: Polyclonal
- Tested Applications: E, IF, IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 0.02 mg | 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: ADAM29 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ADAM29.
The immunogen is located within amino acids 710 - 760 of ADAM29. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E, IF, IHC-P, WB
- APPLICATION NOTE: ADAM29 antibody can be used for detection of ADAM29 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - SPECIFICITY: ADAM29 antibody is human specific. ADAM29 antibody is predicted to not cross-react with other ADAM family proteins.
- POSITIVE CONTROL 1: Cat. No. 1310 - Human Bladder Tissue Lysate
- POSITIVE CONTROL 2: Cat. No. 11-701 - Human Testis Tissue Slide
- PREDICTED MOLECULAR WEIGHT: Predicted: 76 kDa
Observed: 80 kDa
Properties
- PURIFICATION: ADAM29 antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: ADAM29 antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: ADAM29 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: ADAM29
- ADDITIONAL NAMES: Disintegrin and metalloproteinase domain-containing protein 29, ADAM metallopeptidase domain 29, CT73, SVPH1
- Protein Accession Number: NP_055084
- PROTEIN GI NUMBER: 73765552
- NCBI GENE ID NUMBER: 11086
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The ADAM (a disintegrin and metalloprotease) protein family plays a role in cell-cell and cell-matrix interface related processes, including fertilization, muscle fusion, secretion of TNFalpha (tumor necrosis factor alpha), and modulation of the neurogenic function of Notch and Delta (1-3). ADAM29 contains one disintegrin domain, one EGF-like domain and one peptidase M12B domain (2). It is highly expressed in testes (3) and may be involved in spermatogenesis and fertilization (4,5).
- 1: Wang F, Xu R, Zhu P, et al. Preliminarily functional analysis of a cloned novel human gene ADAM29. Sci. China C. Life Sci. 2001; 44392-9.
- 2: Xu R, Cai J, Xu T, et al. Molecular cloning and mapping of a novel ADAM gene (ADAM29) to human chromosome 4. Genomics 1999; 62:537-9.
- 3: Cerretti DP, DuBose RF, Black RA, et al. Isolation of two novel metalloproteinase-disintegrin (ADAM) cDNAs that show testis-specific gene expression. Biochem. Biophys. Res. Commun. 1999; 263:810-5.
- 4: Oppezzo P, Vasconcelos Y, Settegrana C, et al. The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia. Blood 2005; 106:650-7.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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