ADAM23 Antibody
CATALOG NUMBER: 42-033- Clonality: Polyclonal
- Tested Applications: E
- Host Species: Goat
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Goat
- HOMOLOGY: Expected Species Reactivity based on sequence homology: Human
- IMMUNOGEN: The immunogen for this antibody is: NGKPQYSKGGEHC
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave an approx 70kDa band in Human Brain (Cerebellum and Frontal Cortex) lysates after 0.7ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe. The precursor of this glycoprotein has a calculated size of 91.9kDa according to NP_003803.1. The 70kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: ADAM23
- ADDITIONAL NAMES: ADAM23 , ADAM metallopeptidase domain 23 , MDC3, a disintegrin and metalloproteinase domain 23
- Protein Accession Number: NP_003803.1
- PROTEIN GI NUMBER: 4501913
- NCBI GENE ID NUMBER: 8745
Background
- 1: Takada H, Imoto I, Tsuda H, Nakanishi Y, Ichikura T, Mochizuki H, Mitsufuji S, Hosoda F, Hirohashi S, Ohki M, Inazawa J. ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation. Oncogene. 2005 Dec 1;24(54):8051-60.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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