- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant protein of human ACVRL1
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
- POSITIVE CONTROL 1: SH-SY5Y
- POSITIVE CONTROL 2: HL-60
- POSITIVE CONTROL 3: MCF7
- POSITIVE CONTROL 4: Jurkat
- POSITIVE CONTROL 5: Mouse lung
- POSITIVE CONTROL 6: Mouse heart
- PREDICTED MOLECULAR WEIGHT: Observed: 65kDa
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
- NCBI OFFICIAL SYMBOL: ACVRL1
- ADDITIONAL NAMES: ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, activin A receptor type II-like 1, Activin A receptor, type II-like kinase 1
- NCBI GENE ID NUMBER: 94
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
- This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
- FOR RESEARCH USE ONLY
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- Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CATALOG NUMBER: 18-157
- Size: 50 uL
- List Price: $285.00
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