Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: This ACADL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human ACADL.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 48 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ACADL
- ADDITIONAL NAMES: Long-chain specific acyl-CoA dehydrogenase, mitochondrial, LCAD, ACADL
- Protein Accession Number: P28330
- PROTEIN GI NUMBER: 223590148
- NCBI GENE ID NUMBER: 33
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene belongs to the acyl-CoAdehydrogenase family, which is a family of mitochondrialflavoenzymes involved in fatty acid and branched chain amino-acidmetabolism. This protein is one of the four enzymes that catalyzethe initial step of mitochondrial beta-oxidation of straight-chainfatty acid. Defects in this gene are the cause of long-chainacyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotichypoglycemia.
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Maher, A.C., et al. Mol. Genet. Metab. 100(2):163-167(2010)
- 3: Illig, T., et al. Nat. Genet. 42(2):137-141(2010)
- 4: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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