Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine
- IMMUNOGEN: This A2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human A2M.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 163 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: A2M
- ADDITIONAL NAMES: Alpha-2-macroglobulin, Alpha-2-M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, A2M, CPAMD5
- Protein Accession Number: P01023
- PROTEIN GI NUMBER: 308153640
- NCBI GENE ID NUMBER: 2
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Alpha-2-macroglobulin is a protease inhibitor and cytokinetransporter. It inhibits many proteases, including trypsin,thrombin and collagenase. A2M is implicated in Alzheimer disease(AD) due to its ability to mediate the clearance and degradation ofA-beta, the major component of beta-amyloid deposits. [provided byRefSeq].
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Bruno, E., et al. Neurosci. Lett. 482(2):112-116(2010)
- 3: Nalpas, B., et al. Gut 59(8):1120-1126(2010)
- 4: Song, H., et al. Neurosci. Lett. 479(2):143-145(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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