- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: Full-length 3-HKT (Anopheles gambiae) is untagged.
- FUSION TAG: Tag Free
- APPLICATION NOTE: This recombinant proteins is for research use only.
- BIOLOGICAL ACTIVITY: Specific activity towards D,L-3HK: 33 umol/min per mg. Primarily catalyses the pyridoxal 5'-phosphate (PLP)-dependent irreversible transamination of 3-hydroxykynurenine (3-HK) to xanthurenic acid (XA).
- PURITY: >99% (SDS-PAGE)
- PHYSICAL STATE: Liquid
- BUFFER: In 20mM TRIS-HCl pH 8.0, containing 150mM NaCl and 40uM pyridoxal 5'-phosphate (PLP).
- CONCENTRATION: 0.5mg/ml (Lot specific)
- STORAGE CONDITIONS: Stable for at least 6 months after receipt when stored at -80°C.
- NCBI OFFICIAL SYMBOL: AgaP_AGAP010387
- ADDITIONAL NAMES: 3-HKT, EC 2.6.1
- Protein Accession Number: Q7PRG3
- PROTEIN GI NUMBER: 74839042
- NCBI GENE ID NUMBER: 1272658
- The 3-hydroxykynurenine transaminase (3-HKT) gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of microgametocytes in the midgut of malaria vector species. The 3-HKT enzyme is involved in the tryptophan metabolism of Anophelines. The gene had been studied in the important global malaria vector, Anopheles gambiae.
- FOR RESEARCH USE ONLY
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CATALOG NUMBER: 90-358
- Size: 50 ug
- List Price: $535.00
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