PPP1R9A Antibody Cat. No.: 60-138

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: This PPP1R9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 455-484 amino acids from the Central region of human PPP1R9A.
TESTED APPLICATIONS: WB
APPLICATIONS: For WB starting dilution is: 1:1000
PREDICTED MOLECULAR WEIGHT: 123 kDa

psi-iconProperties
PURIFICATION:This antibody is purified through a protein A column, followed by peptide affinity purification.
CLONALITY:Polyclonal
ISOTYPE:Rabbit Ig
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:PPP1R9A
ALTERNATE NAMES:Neurabin-1, Neurabin-I, Neural tissue-specific F-actin-binding protein I, Protein phosphatase 1 regulatory subunit 9A, PPP1R9A, KIAA1222
ACCESSION NO.:Q9ULJ8
PROTEIN GI NO.:50403806
GENE ID:55607
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
REFERENCES:1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
2) Suarez-Gestal, M., et al. Arthritis Res. Ther. 12 (2), R72 (2010) :
3) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
4) Nakabayashi, K., et al. J. Med. Genet. 41(8):601-608(2004)

ANTIBODIES FOR RESEARCH USE ONLY.

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