PDL2 Detection Set (Risk Free) Cat. No.: RF16020

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psi-iconSpecifications
SPECIES REACTIVITY:Human
TESTED APPLICATIONS:ELISA, Flow, ICC, IF, IHC-P, WB
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
IMMUNOGEN:Mouse monoclonal PD-L2 antibodies were raised against the extracellular domain of human PD-L2.
HOST SPECIES:Mouse
psi-iconSet Contents
Catalog Number RF16021Catalog number RF16021 — PDL2 Antibody [4E10]
Catalog Number RF16022Catalog number RF16022 — PDL2 Antibody [8C12]
Catalog Number RF16023Catalog number RF16023 — PDL2 Antibody [7C7]
Catalog Number RF16024Catalog number RF16024 — PDL2 Antibody [7C1]
Catalog Number RF16025Catalog number RF16025 — PDL2 Antibody [10H6]
psi-iconProperties
PHYSICAL STATE:Liquid
BUFFER:PBS containing 0.02% sodium azide.
CONCENTRATION:Antibody 1 mg/mL
STORAGE CONDITIONS:Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Monoclonal
ISOTYPE:IgG1
CONJUGATE:Unconjugated
psi-iconAdditional Info
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground
BACKGROUND:Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through an alternative receptor from PD-1. ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

DETECTION-SETS FOR RESEARCH USE ONLY.

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