PDL1 Detection Set (Risk Free) Cat. No.: RF16030

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psi-iconSpecifications
SPECIES REACTIVITY:Human
TESTED APPLICATIONS:ELISA, Flow, ICC, IF, IHC-P, WB
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
IMMUNOGEN:PD-L1 antibodies were raised against the extracellular domain of human PD-L1.
HOST SPECIES:Mouse
psi-iconSet Contents
Catalog Number RF16031Catalog number RF16031 — PDL1 Antibody [4F2]
Catalog Number RF16032Catalog number RF16032 — PDL1 Antibody [8E12]
Catalog Number RF16033Catalog number RF16033 — PDL1 Antibody [5H6]
Catalog Number RF16035Catalog number RF16035 — PDL1 Antibody [6H10]
Catalog Number RF16036Catalog number RF16036 — PDL1 Antibody [2D6]
Catalog Number RF16037Catalog number RF16037 — PDL1 Antibody [1F11]
Catalog Number RF16038Catalog number RF16038 — PDL1 Antibody [1D7]
psi-iconProperties
PHYSICAL STATE:Liquid
BUFFER:PBS containing 0.02% sodium azide.
CONCENTRATION:Antibody 1 mg/mL
STORAGE CONDITIONS:Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Monoclonal
ISOTYPE:IgG1
CONJUGATE:Unconjugated
psi-iconAdditional Info
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground
BACKGROUND:Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts. ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

DETECTION-SETS FOR RESEARCH USE ONLY.

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