PARP-2 [ARTD2] high purity Recombinant Protein Cat. No.: 90-341

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psi-iconSpecifications
SPECIES:Mouse
SOURCE SPECIES:Sf21 cells
SEQUENCE:Mouse full-length PARP-2 [ARTD2] is fused to a His-tag.
FUSION TAG:His Tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant proteins is for research use only.
BIOLOGICAL ACTIVITY: >600U/mg protein.
psi-iconProperties
PURITY:>98% (SDS-PAGE)
PHYSICAL STATE:Liquid
BUFFER:In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol.
CONCENTRATION:Lot dependent (0.2-1mg/ml)
STORAGE CONDITIONS:Stable for at least 6 months after receipt when stored at -80˚C.
psi-iconAdditional Info
ALTERNATE NAMES:Poly(ADP-ribose) Polymerase, ADP-ribosyltransferase Diphtheria Toxin-like 2, NAD(+) ADP-ribosyltransferase 2
ACCESSION NO.:O88554
PROTEIN GI NO.:17380186
OFFICIAL SYMBOL:Parp2
GENE ID:11546
psi-iconBackground and References
BACKGROUND:PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

FOR RESEARCH USE ONLY.

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