PACS-1 Antibody Cat. No.: 33-026

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse
IMMUNOGEN: A recombinant protein fragment from the intermal portion of human PACS-1 was used as the immunogen for this antibody.
TESTED APPLICATIONS: WB
APPLICATIONS: Western blot: 1-3 ug/ml

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

psi-iconProperties
PURIFICATION:Protein A affinity chromatography
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.1 mg/ml BSA and 0.05% sodium azide
CONCENTRATION:0.5 mg/mL
STORAGE CONDITIONS:Aliquot and Store at -20˚C. Avoid freez-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:PACS1
ALTERNATE NAMES:Phosphofurin acidic cluster sorting protein 1, PACS-1, MRD17
GENE ID:55690
USER NOTE:Optimal dilutions for each application to be determined by the researcher
psi-iconBackground and References
BACKGROUND:PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor). PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.

ANTIBODIES FOR RESEARCH USE ONLY.

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