p62 Recombinant Protein Cat. No.: 39-906

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:This recombinant protein can be used for WB, ELISA.
BIOLOGICAL ACTIVITY: N/A
psi-iconProperties
PURITY:>90%
PHYSICAL STATE:Liquid
BUFFER:20mM Tris-HCl, 150mM NaCl, 1mM EDTA, 5mM Glutathione, 0.5mM GSSH and 10% Glycerol.
STORAGE CONDITIONS:Store in working aliquots at -80˚C. Avoid freeze/thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:nuclear pore glycoprotein p62, nucleoporin Nup62, 62 kDa nucleoporin, p62, IBSN, SNDI, Nuclear pore glycoprotein p62
ACCESSION NO.:NP_001180286.1
PROTEIN GI NO.:301069416
OFFICIAL SYMBOL:NUP62
GENE ID:23636
psi-iconBackground and References
BACKGROUND:Protein p62 preferentially binds multiubiquitin chains and forms a novel cytoplasmic structure "sequestosome" which serves as a storage place for ubiquitinated proteins.
REFERENCES:1) Eng M Tan (1999). A Novel Cytoplasmic Protein with RNA-binding Motifs is an Autoantigen in Human Hepatocellular Carcinoma. J Exp Med 189 (7): 1101-1110
2) Moscat J (2005). The p62 scaffold regulates nerve growth factor -induced NF-kapppa B activation by influencing TRAF6 polyubiquitination. J Biol Chem 280 (42) 35625-9

FOR RESEARCH USE ONLY.

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