OX40L multimeric Recombinant Protein Cat. No.: 90-239

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psi-iconSpecifications
SPECIES:Human, Mouse
SOURCE SPECIES:HEK293 cells
SEQUENCE:The extracellular domain of mouse OX40L (aa 52-199) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a DDDDK-tag.
FUSION TAG:DDDDK Tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant proteins is for research use only.
BIOLOGICAL ACTIVITY: Activates T cell proliferation.
psi-iconProperties
PURITY:>90% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
PHYSICAL STATE:Lyophilized
BUFFER:Contains PBS. Reconstitute with 100 μl sterile water.
CONCENTRATION:0.1mg/ml after reconstitution.
STORAGE CONDITIONS:Stable for at least 6 months after receipt when stored at -20˚C.
psi-iconAdditional Info
ALTERNATE NAMES:ACRP30headless:OX40L, ACRP30headless:CD252, ACRP30headless:CD134L
ACCESSION NO.:P43488
OFFICIAL SYMBOL:Tnfsf4
GENE ID:22164
psi-iconBackground and References
BACKGROUND:OX40L [CD252; CD134L] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MultimericOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation.

FOR RESEARCH USE ONLY.

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