This recombinant protein can be used for E, WB. For research use only.
BIOLOGICAL ACTIVITY:
Measured by its binding ability in a functional ELISA. Immobilized Rhesus macaque OX40, His Tag at 2 ug/mL (100 uL/well) can bind Human OX40 Ligand, Fc Tag with a linear range of 0.2-25 ng/mL (QC tested).
Properties
PURITY:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:
22.1 kDa
PHYSICAL STATE:
Lyophilized
BUFFER:
PBS, pH7.4
STORAGE CONDITIONS:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Additional Info
ALTERNATE NAMES:
TNFRSF4,OX40,CD134,OX40L receptor,ACT35,TXGP1L
ACCESSION NO.:
XP_001090870.1
OFFICIAL SYMBOL:
OX40
GENE ID:
699674
Background and References
BACKGROUND:
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.
REFERENCES:
1) Arch R.H., et al., 1998, Mol. Cell. Biol. 18:558-565.
2) Kawamata S., et al., 1998, J. Biol. Chem. 273:5808-5814.