Specifications
| HOST SPECIES: | Rabbit |
| SPECIES REACTIVITY: |
Dog, Human, Mouse, Rat |
| IMMUNOGEN: |
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEUROD2. |
| TESTED APPLICATIONS: |
ELISA, WB |
| APPLICATIONS: |
NEUROD2 antibody can be used for detection of NEUROD2 by ELISA at 1:62500. NEUROD2 antibody can be used for detection of NEUROD2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| POSITIVE CONTROL: | 1) Tranfected 293T Cell Lysate |
| PREDICTED MOLECULAR WEIGHT: |
41 kDa |
Properties
| PURIFICATION: | Antibody is purified by protein A chromatography method. |
| CLONALITY: | Polyclonal |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| CONCENTRATION: | batch dependent |
| STORAGE CONDITIONS: | For short periods of storage (days) store at 4˚C. For longer periods of storage, store NEUROD2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
Additional Info
| OFFICIAL SYMBOL: | NEUROD2 |
| ALTERNATE NAMES: | NEUROD2, NDRF, bHLHa1 |
| ACCESSION NO.: | NP_006151 |
| PROTEIN GI NO.: | 98986461 |
| GENE ID: | 4761 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
Background and References
| BACKGROUND: | NEUROD2 is a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of NEUROD2 can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. |
| REFERENCES: | 1) Westerman, B.A., (2004) Biochim. Biophys. Acta 1676 (1), 96-103. |
ANTIBODIES FOR RESEARCH USE ONLY.
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