Nalp12 / Nlrp12 Antibody Cat. No.: 43-426

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psi-iconSpecifications
HOST SPECIES:Goat
SPECIES REACTIVITY: Mouse
HOMOLOGY: Expected Species Reactivity based on sequence homology: Rat
IMMUNOGEN: The immunogen for this antibody is: C-KPGTPTFKVPANQR
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 100kDa band observed in Mouse Liver and Spleen lysates (calculated MW of 119kDa according to NP_001028603.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Jéru et al, Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1614-9.PMID: 18230725). Recommended concentration: 1-3ug/ml.
PREDICTED MOLECULAR WEIGHT: Approx 100kDa

psi-iconProperties
PURIFICATION:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
CONCENTRATION:500 ug/mL
STORAGE CONDITIONS:Aliquot and store at -20˚C. Minimize freezing and thawing.

psi-iconAdditional Info
OFFICIAL SYMBOL:Nalp12 / Nlrp12
ALTERNATE NAMES:Nlrp12, NLR family, pyrin domain containing 12, Nalp12, PYPAF7, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, PYRIN-containing APAF1-like protein 7, monarch-1
ACCESSION NO.:NP_001028603.1
PROTEIN GI NO.:257468329
GENE ID:378425
psi-iconBackground and References
REFERENCES:1) Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP.NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling.

ANTIBODIES FOR RESEARCH USE ONLY.

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