| HOST SPECIES: | Rabbit |
| SPECIES REACTIVITY: | Human, Mouse, Rat |
| IMMUNOGEN: | MOSPD1 antibody was raised against a 19 amino acid peptide near the center of human MOSPD1 . The immunogen is located within amino acids 110 - 160 of MOSPD1. |
| TESTED APPLICATIONS: | ELISA, IF, IHC-P, WB |
| APPLICATIONS: | MOSPD1 Antibody can be used for detection of MOSPD1 by Western blot at 1 μg/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. |
| POSITIVE CONTROL: | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
| PREDICTED MOLECULAR WEIGHT: | Predicted: 23 kDa Observed: 25 kDa |
Specifications| PURIFICATION: | MOSPD1 Antibody is affinity chromatography purified via peptide column. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | IgG |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | MOSPD1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| CONCENTRATION: | 1 mg/mL |
| STORAGE CONDITIONS: | MOSPD1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| OFFICIAL SYMBOL: | MOSPD1 |
| ALTERNATE NAMES: | MOSPD1 Antibody: DJ473B4, Motile sperm domain-containing protein 1 |
| ACCESSION NO.: | NP_062456 |
| PROTEIN GI NO.: | 9506543 |
| GENE ID: | 56180 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
| BACKGROUND: | MOSPD1 Antibody: The Motile sperm domain-containing protein 1 (MOSPD1) is part of a family of proteins defined by the presence of a major sperm protein (MSP) domain and two transmembrane domains. MOSPD1 codes for a small protein that localizes to the endoplasmic reticulum (ER) and the Golgi apparatus and has been suggested to play a role in the developmental regulation at the switch between mesenchymal and epithelial cells. |
| REFERENCES: | 1) Pall GS, Wallis J, Axton R, et al. A novel transmembrane MSP-containing protein that plays a role in the right ventricle development. Genomics 2004; 84:1051-9. | 2) Thaler R, Rumpler M, Spitzer S, et al. Mospd1, a new player in mesenchymal versus epidermal cell differentiation. J. Cell Physiol. 2011; 226:2505-15. |
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