MMP14 Antibody Cat. No.: XW-7751

Availability: In stock

$0.00

No Image

 Price Options

$0.00
psi-iconSpecifications
HOST SPECIES:Chicken
SPECIES REACTIVITY: Bovine, Human, Rat
IMMUNOGEN: 126-230
TESTED APPLICATIONS: WB
APPLICATIONS: Matrix metalloproteinase-14 antibody can be used for the detection of Matrix metalloproteinase-14 by Western Blot.
PREDICTED MOLECULAR WEIGHT: 65.9 kDa (calculated)

psi-iconProperties
PURIFICATION:Immunoaffinity Purified
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Phosphate-Buffered Saline. No preservatives added.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:MMP14 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:MMP14
ALTERNATE NAMES:Matrix metalloproteinase-14MMP-14, MMP-14, MMP-X1, MT-MMP, MT1MMP, MTMMP1, WNCHRS, MT1-MMP, MT-MMP 1, Matrix metalloproteinase14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase
ACCESSION NO.:NP_004986.1
PROTEIN GI NO.:4826834
GENE ID:4323
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:FUNCTION: Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface.

CATALYTIC ACTIVITY: Endopeptidase activity. Activates progelatinase A by cleavage of the propeptide at 37-Asn-|-Leu-38. Other bonds hydrolyzed include 35-Gly-|-Ile-36 in the propeptide of collagenase 3, and 341-Asn-|-Phe-342, 441-Asp-|-Leu-442 and 354-Gln-|-Thr-355 in the aggrecan interglobular domain.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.