SPECIES: | Human |
SOURCE SPECIES: | E. coli |
SEQUENCE: | Met1-Phe121 |
FUSION TAG: | C-6 His tag |
TESTED APPLICATIONS: | |
APPLICATIONS: | This recombinant protein can be used for biological assays. For research use only. |
PURITY: | Greater than 95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
PREDICTED MOLECULAR WEIGHT: | 15.3 kD |
PHYSICAL STATE: | Liquid |
BUFFER: | Supplied as a 0.2 um filtered solution of 20mM Tris, 20% Glycerol, 0.1M NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. |
STORAGE CONDITIONS: | Store at -20˚C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
ALTERNATE NAMES: | Microtubule-Associated Proteins 1A/1B Light Chain 3A, Autophagy-Related Protein LC3 A, Autophagy-Related Ubiquitin-Like Modifier LC3 A, MAP1 Light Chain 3-Like Protein 1, MAP1A/MAP1B Light Chain 3 A, MAP1A/MAP1B LC3 A, Microtubule-Associated Protein 1 Light Chain 3 Alpha, MAP1LC3A |
ACCESSION NO.: | Q9H492 |
PROTEIN GI NO.: | 530379522 |
OFFICIAL SYMBOL: | MAP1LC3A |
GENE ID: | 84557 |
BACKGROUND: | Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) belongs to the MAP1 LC3 family. MAP1LC3A is found most abundantly in the heart, brain, liver, skeletal muscle, and testis. But it is absent in the thymus and peripheral blood leukocytes. MAP1LC3A is thought to take part in the formation of autophagosomal vacuoles and is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. In addition, MAP1A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. |
FOR RESEARCH USE ONLY.
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