LYZL1 Antibody Cat. No.: 6947

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: LYZL1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human.

The immunogen is located within the first 50 amino acids of LYZL1.
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: LYZL1 antibody can be used for detection of LYZL1 by Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
SPECIFICITY: At least two alternatively spliced transcript variants have been observed.
POSITIVE CONTROL:1) Cat. No. 1288 - A20 Cell Lysate
PREDICTED MOLECULAR WEIGHT: 21 kDa

psi-iconProperties
PURIFICATION:LYZL1 Antibody is affinity chromatography purified via peptide column.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:LYZL1 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:LYZL1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:LYZL1
ALTERNATE NAMES:LYZL1 Antibody: LYC2, KAAG648, PRO1278, bA534G20.1, LYC2, UNQ648/PRO1278, Lysozyme-like protein 1
ACCESSION NO.:NP_115906
PROTEIN GI NO.:73390143
GENE ID:84569
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:LYZL1 Antibody: The lysozyme family of proteins has an important role in host defense and is associated with the monocyte-macrophage system and enhances the activity of immunoagents. The mammalian lysozyme gene family is much larger than previously appreciated and consists of at least eight distinct genes scattered around the genome. C-type lysozymes are specifically involved catalyzing the hydrolysis of β-1,4 glycosidic bonds of the peptidoglycan of bacterial cell walls. As a homolog of human C-type lysozyme, LYZL1 is an intra-acrosomal, nonbacteriolytic, c lysozyme-like protein recently isolated from human spermatozoa.
REFERENCES:1) Peters CW, Kruse U, Pollwein R, et al. The human lysozyme gene. Sequence organization and chromosomal localization. Eur. J. Biochem. 1989; 182:507-16.
2) Irwin DM, Biegel JM, and Stewart CB. Evolution of the mammalian lysozyme gene family. BMC Evol. Biol. 2011; 11:166.
3) Zhang K, Gao R, Zhang H, et al. Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/α-lactalbumin family. Biol. Reprod. 2005; 73:1064-71.
4) Mandal A, Klotz KL, Shetty J, et al. SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. Biol. Reprod. 2003; 68:1525-37.

ANTIBODIES FOR RESEARCH USE ONLY.

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