Datasheet

LIAR Antibody
CATALOG NUMBER: 5261

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Human, Mouse, Rat
HOMOLOGY:Predicted species reactivity based on immunogen sequence: Bovine: (94%)
TESTED APPLICATIONS:ELISA, IF, IHC-P, WB
APPLICATIONS:LIAR antibody can be used for detection of LIAR by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
POSITIVE CONTROL:1) Cat. No. 1405 - Mouse Kidney Tissue Lysate
IMMUNOGEN:LIAR antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human LIAR.

The immunogen is located within amino acids 230 - 280 of LIAR.
HOST SPECIES:Rabbit

Properties

PURIFICATION:LIAR Antibody is affinity chromatography purified via peptide column.
PHYSICAL STATE:Liquid
BUFFER:LIAR Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:LIAR antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:LIAR Antibody: LIAR, LIAR, Ankyrin repeat domain-containing protein 54, Lyn-interacting ankyrin repeat protein
ACCESSION NO.:NP_620152
PROTEIN GI NO.:20270347
OFFICIAL SYMBOL:ANKRD54
GENE ID:129138

Background

BACKGROUND:LIAR Antibody: Ankyrin (ANK) repeats mediate protein-protein interactions in diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20. ANK repeats may occur in combinations with other types of domains. The structural repeat unit contains two anti-parallel helices and a beta-hairpin, with repeats stacked in a superhelical arrangement. LIAR, also known as ANKRD54, is a recently identified ANK repeat-containing protein that is predominantly expressed in tissues rich in cilliated cells, such as olfactory sensory neurons and is predicted to be important to cilia. At least three isoforms of LIAR are known to exist.
REFERENCES: 1) Li J, Mahajan A, and Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry2006; 45:15168-78.

For Research Use Only