This recombinant protein can be used for WB. For research use only.
BIOLOGICAL ACTIVITY:
Measured by its binding ability in a functional ELISA. When rhLAMP1 /CD107a is coated at 1 μg/mL, rhGalectin‑3 binds with an apparent KD <30 nM.
Properties
PURITY:
>95% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:
39.2 kDa
PHYSICAL STATE:
Lyophilized
BUFFER:
PBS, pH7.4
STORAGE CONDITIONS:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Additional Info
ALTERNATE NAMES:
LAMP1, CD107a
ACCESSION NO.:
NP_005552
OFFICIAL SYMBOL:
LAMP1
GENE ID:
3916
Background and References
BACKGROUND:
Lysosomal-associated membrane protein 1 (LAMP1) is also known as CD107a (Cluster of Differentiation 107a). LAMP1 / CD107a belongs to the LAMP family. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells.
REFERENCES:
1) Chang MH., et al., J. Biol. Regul. Homeost. Agents 16 (2): 147–51.
2) Carlsson S.R., et al., 1993, Arch. Biochem. Biophys. 304:65-73.