LAG-3 Antibody [17B4] (ATTO 590) Cat. No.: 36-111

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Human
IMMUNOGEN: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
TESTED APPLICATIONS: ICC
SPECIFICITY: Recognizes human LAG-3.

psi-iconProperties
PURIFICATION:>95% (SDS-PAGE)
CLONALITY:Monoclonal
ISOTYPE:IgG1
CONJUGATE:ATTO 590
PHYSICAL STATE:Liquid
BUFFER:Liquid. In PBS containing 0.02% sodium azide.
CONCENTRATION:0.5 mg/ml
STORAGE CONDITIONS:Keep conjugated formats at +4˚C. Stable for at least 1 year after receipt when stored at +4˚C.

psi-iconAdditional Info
OFFICIAL SYMBOL:LAG3
ALTERNATE NAMES:Lymphocyte Activation Gene-3; FDC Protein; CD223
ACCESSION NO.:251757512
PROTEIN GI NO.:P18627
GENE ID:3902
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

ANTIBODIES FOR RESEARCH USE ONLY.

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