JAKMIP2 Antibody Cat. No.: 7167

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse
IMMUNOGEN: Rabbit polyclonal JAKMIP2 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP2.

The immunogen is located within amino acids 250 - 300 of JAKMIP2.
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: JAKMIP2 antibody can be used for detection of JAKMIP2 by Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
SPECIFICITY: At least four isoforms of JAKMIP2 are known to exist; this antibody will detect all four isoforms. JAKMIP2 antibody is predicted to not cross-react with JAKMIP1.
POSITIVE CONTROL:1) Cat. No. 1403 - Mouse Brain Tissue Lysate
PREDICTED MOLECULAR WEIGHT: Predicted: 89 kDa

psi-iconProperties
PURIFICATION:JAKMIP2 Antibody is affinity chromatography purified via peptide column.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:JAKMIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:JAKMIP2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

psi-iconAdditional Info
OFFICIAL SYMBOL:JAKMIP2
ALTERNATE NAMES:JAKMIP2 Antibody: NECC1, JAMIP2, KIAA0555, NECC1, Janus kinase and microtubule-interacting protein 2, CTCL tumor antigen HD-CL-04
ACCESSION NO.:NP_055605
PROTEIN GI NO.:45237195
GENE ID:9832
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:JAKMIP2 Antibody: JAKMIP2, also known as neuroendocrine long coiled-coil protein 1 (NECC1), is a member of the JAKMIP family of proteins whose members are thought play a role in JAK1 signaling and the regulation of microtubule cytoskeleton rearrangements. JAKMIP2 is expressed predominantly in neuronal cells but unlike JAKMIP1, JAKMIP2 localizes to the Golgi complex. It has been suggested that JAKMIP2 may play important roles in the control of the regulated secretory pathway.
REFERENCES:1) Steindler C, Li Z, Algarte M, et al. Jamip1 (Marlin-1) defines a family of proteins interacting with Janus kinases and microtubules. J. Biol. Chem. 2004; 279:43168-77.
2) Cruz-Garcia D, Vazquez-Martinez R, Peinado JR, et al. Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins. FEBS Lett. 2007; 581:3149-56.

ANTIBODIES FOR RESEARCH USE ONLY.

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