Datasheet

JAKMIP2 Antibody
CATALOG NUMBER: 7167

Availability: In stock

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Human, Mouse
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:JAKMIP2 antibody can be used for detection of JAKMIP2 by Western blot at 1 - 2 μg/mL.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
POSITIVE CONTROL:1) Cat. No. 1403 - Mouse Brain Tissue Lysate
PREDICTED MOLECULAR WEIGHT:Predicted: 89 kDa
SPECIFICITY:At least four isoforms of JAKMIP2 are known to exist; this antibody will detect all four isoforms. JAKMIP2 antibody is predicted to not cross-react with JAKMIP1.
IMMUNOGEN:Rabbit polyclonal JAKMIP2 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP2.

The immunogen is located within amino acids 250 - 300 of JAKMIP2.
HOST SPECIES:Rabbit

Properties

PURIFICATION:JAKMIP2 Antibody is affinity chromatography purified via peptide column.
PHYSICAL STATE:Liquid
BUFFER:JAKMIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:JAKMIP2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:JAKMIP2 Antibody: NECC1, JAMIP2, KIAA0555, NECC1, Janus kinase and microtubule-interacting protein 2, CTCL tumor antigen HD-CL-04
ACCESSION NO.:NP_055605
PROTEIN GI NO.:45237195
OFFICIAL SYMBOL:JAKMIP2
GENE ID:9832

Background

BACKGROUND:JAKMIP2 Antibody: JAKMIP2, also known as neuroendocrine long coiled-coil protein 1 (NECC1), is a member of the JAKMIP family of proteins whose members are thought play a role in JAK1 signaling and the regulation of microtubule cytoskeleton rearrangements. JAKMIP2 is expressed predominantly in neuronal cells but unlike JAKMIP1, JAKMIP2 localizes to the Golgi complex. It has been suggested that JAKMIP2 may play important roles in the control of the regulated secretory pathway.
REFERENCES: 1) Steindler C, Li Z, Algarte M, et al. Jamip1 (Marlin-1) defines a family of proteins interacting with Janus kinases and microtubules. J. Biol. Chem. 2004; 279:43168-77.
2) Cruz-Garcia D, Vazquez-Martinez R, Peinado JR, et al. Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins. FEBS Lett. 2007; 581:3149-56.

For Research Use Only